In 2018, Europe experienced an upsurge in the number of WNV infections. S., more human cases were seen in 2018 when compared to the previous year(s).
The natural transmission cycle of WNV involves certain mosquito species, mainly , and a number of avian species.
To reconstruct the evolutionary dynamics and epidemiological history of the virus in Italy, 53 envelope gene and 26 complete genome sequences obtained from human and animal samples were characterised by means of next-generation sequencing.
Phylogenetic analysis revealed two Italian strains originating between 20: clade A, which apparently became extinct in 2013–2014, and clade B, which was responsible for the 2018 epidemic.
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The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs).The main geographical subclades, B1, B2 and B5, are highlighted.Full article "Figure 4 Mean p-distance between years 20 in clade B Italian isolates.The mean genetic distance within each group grows longer over time with the greatest divergence in the years 20.Full article "Figure 5 Analysis of 127 European complete genome sequences.Since transmission-competent mosquito species are abundantly found in cooler climatic regions, further dispersal of the virus is likely.In this Special Issue, we welcome research papers and review articles related to all aspects of WNV research, providing an update of our knowledge of WNV. Norbert Nowotny Manuscript Submission Information Manuscripts should be submitted online at com by registering and logging in to this website. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website.Please select whether you prefer to view the MDPI pages with a view tailored for mobile displays or to view the MDPI pages in the normal scrollable desktop version.This selection will be stored into your cookies and used automatically in next visits.Topics of interest include (but are not limited to) virus genetics, epidemiology, virus–host interactions, pathogenesis, vaccine development, improvement in diagnostics, as well as vector entomology. Once you are registered, click here to go to the submission form. Research articles, review articles as well as short communications are invited.For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.